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Euler 
 conjectured that there are no Positive Integer solutions to the quartic Diophantine
Equation
See also Diophantine Equation--Quartic
References
Berndt, B. C. and Bhargava, S. ``Ramanujan--For Lowbrows.''  Amer. Math. Monthly 100, 644-656, 1993.
 
Guy, R. K.  Unsolved Problems in Number Theory, 2nd ed.
  New York: Springer-Verlag, pp. 139-140, 1994.
 
Lander, L. J.; Parkin, T. R.; and Selfridge, J. L.  ``A Survey of Equal Sums of Like Powers.''  Math. Comput. 21, 446-459, 1967.
 
Ward, M.  ``Euler's Problem on Sums of Three Fourth Powers.''  Duke Math. J. 15, 827-837, 1948.