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The center of any Sphere which has a contact of (at least) first-order with a curve 
 at a point 
 lies
in the normal plane to 
 at 
.  The center of any Sphere which has a contact of (at least) second-order with 
at point 
, where the Curvature 
, lies on the polar axis of 
 corresponding to 
.  All these
Spheres intersect the Osculating Plane of 
 at 
 along a circle of curvature at 
.  
The osculating sphere has center
See also Curvature, Osculating Plane, Radius of Curvature, Sphere, Torsion (Differential Geometry)
References
Kreyszig, E.  Differential Geometry.  New York: Dover, pp. 54-55, 1991.